Assay Detail
Binding
CHEMBL4308963
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Inhibition of mTORC1 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.52 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1801204 | AZD-8055 | 1.0 | 1 | 9.10 |
| CHEMBL4563142 | — | — | 1 | 9.00 |
| CHEMBL561708 | — | — | 1 | 8.30 |
| CHEMBL1242115 | — | — | 1 | 8.10 |
| CHEMBL1241674 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1801204 | AZD-8055 | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL4563142 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL561708 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL1242115 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL1241674 | — | IC50 | = | 8.0 | nM | 8.10 |