Assay Detail
Binding
CHEMBL4308975
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of recombinant human AMPK alpha1/beta1/gamma1expressed in Escherichia coli BL21-codon plus(DE3)-RIL using SAMS peptide as substrate after 10 mins in presence of gamma-[33]P-ATP by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 (CHEMBL2111345) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1242297 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1242297 | — | EC50 | = | 300.0 | nM | 6.52 |