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Assay Detail

CHEMBL4309995

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK4/cyclin D1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 4/cyclin D1 (CHEMBL1907601)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
Jorda R, Hendrychová D, Voller J, Řezníčková E, Gucký T, Kryštof V.
J Med Chem (2018) 61 : 9105 -9120
PubMed 30234987 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290904 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290904 IC50 = 6000.0 nM 5.22