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Assay Detail

CHEMBL4310367

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Binding
Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl beta-D-glucopyranoside as substrate measured after 20 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Alpha glucosidase (CHEMBL3833502)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Synthesis, in vitro and in vivo evaluation of 2-aryl-4H-chromene and 3-aryl-1H-benzo[f]chromene derivatives as novel α-glucosidase inhibitors.
Spasov AA, Babkov DA, Osipov DV, Klochkov VG, Prilepskaya DR, Demidov MR, Osyanin VA, Klimochkin YN.
Bioorg Med Chem Lett (2019) 29 : 119 -123
PubMed 30340897 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.27 4.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL200715 (-)-CATECHIN 1 4.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL200715 (-)-CATECHIN IC50 = 53800.0 nM 4.27