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Assay Detail

CHEMBL4310419

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania amazonensis MHOM/BR/76/LTB-012 axenic amastigotes after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania amazonensis
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania amazonensis (CHEMBL612877)
Type ORGANISM
Organism Leishmania amazonensis

Publication

Leishmania treatment and prevention: Natural and synthesized drugs.
Bekhit AA, El-Agroudy E, Helmy A, Ibrahim TM, Shavandi A, Bekhit AEA.
Eur J Med Chem (2018) 160 : 229 -244
PubMed 30342363 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.60 7.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4530530 1 7.60
CHEMBL1917526 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4530530 IC50 = 25.0 nM 7.60
CHEMBL1917526 IC50 < 50.0 nM -