Assay Detail
Functional
CHEMBL4310644
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Cytotoxicity against human K562 cells after 72 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Towards lead compounds as anti-cancer agents via new phaeosphaeride A derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.06 | 5.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4475941 | — | — | 1 | 5.37 |
| CHEMBL4455134 | — | — | 1 | 5.35 |
| CHEMBL3633245 | — | — | 1 | 5.16 |
| CHEMBL4468630 | — | — | 1 | 5.07 |
| CHEMBL4467698 | — | — | 1 | 5.03 |
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 5.03 |
| CHEMBL4444185 | — | — | 1 | 4.75 |
| CHEMBL3632630 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4475941 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL4455134 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL3633245 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL4468630 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL4467698 | — | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL4444185 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL3632630 | — | IC50 | = | 20000.0 | nM | 4.70 |