Assay Detail
Binding
CHEMBL4311246
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Aeromonas hydrophila ATCC 7966 CphA expressed in Escherichia coli LMG194 using CPC-1 as substrate preincubated for 10 mins followed by substrate addition by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Aeromonas hydrophila subsp. hydrophila ATCC 7966 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A carbapenem-based fluorescence assay for the screening of metallo-β-lactamase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.66 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1597 | DIMERCAPROL | 4.0 | 1 | 5.11 |
| CHEMBL284104 | DIPICOLINIC ACID | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1597 | DIMERCAPROL | IC50 | = | 7800.0 | nM | 5.11 |
| CHEMBL284104 | DIPICOLINIC ACID | IC50 | = | 61500.0 | nM | 4.21 |