Assay Detail
Binding
CHEMBL4311250
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Aeromonas hydrophila ATCC 7966 NDM1 expressed in Escherichia coli LMG194 using FC3 as substrate preincubated for 10 mins followed by substrate addition by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Aeromonas hydrophila subsp. hydrophila ATCC 7966 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A carbapenem-based fluorescence assay for the screening of metallo-β-lactamase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.61 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1597 | DIMERCAPROL | 4.0 | 1 | 6.00 |
| CHEMBL284104 | DIPICOLINIC ACID | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1597 | DIMERCAPROL | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL284104 | DIPICOLINIC ACID | IC50 | = | 6200.0 | nM | 5.21 |