Assay Detail
Functional
CHEMBL4313832
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against promastigote form of Leishmania major assessed as parasite growth inhibition
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania major |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.17 | 5.17 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4464312 | — | — | 1 | 5.17 |
| CHEMBL125 | MILTEFOSINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4464312 | — | EC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL125 | MILTEFOSINE | Inhibition | - | % | - |