Assay Detail
Functional
CHEMBL4315191
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Antiproliferative activity against human OPM2 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OPM-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.32 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 5.54 |
| CHEMBL4554522 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL4554522 | — | EC50 | = | 7900.0 | nM | 5.10 |