Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4315225

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against TAMH cells incubated for 24 hrs by CellTiter-Glo Cell Viability Assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type TAMH
Confidence 1 — Organism
Curated By Autocuration

Target

TAMH (CHEMBL4483280)
Type CELL-LINE
Organism Mus musculus

Publication

Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.
Soumyanarayanan U, Ramanujulu PM, Mustafa N, Haider S, Fang Nee AH, Tong JX, Tan KSW, Chng WJ, Dymock BW.
Eur J Med Chem (2019) 184 : 111755 -111755
PubMed 31627059 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.54 4.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4554522 1 4.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4554522 EC50 = 29000.0 nM 4.54