Assay Detail
Functional
CHEMBL4316693
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Cytotoxicity against human SKOV3 cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nitro-Group-Containing Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.02 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL570892 | — | — | 1 | 6.77 |
| CHEMBL585336 | — | — | 1 | 6.68 |
| CHEMBL571111 | — | — | 1 | 6.36 |
| CHEMBL568792 | — | — | 1 | 6.30 |
| CHEMBL144896 | — | — | 1 | 5.96 |
| CHEMBL1256927 | — | — | 1 | 5.75 |
| CHEMBL1256965 | — | — | 1 | 5.75 |
| CHEMBL2158186 | — | — | 1 | 5.68 |
| CHEMBL1256966 | — | — | 1 | 5.51 |
| CHEMBL1256989 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL570892 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL585336 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL571111 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL568792 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL144896 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL1256927 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL1256965 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL2158186 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL1256966 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL1256989 | — | IC50 | = | 3300.0 | nM | 5.48 |