Assay Detail
Functional
CHEMBL4316722
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Antiproliferative activity against human NCI-H460 cells in presence of N2
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nitro-Group-Containing Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.40 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4530380 | — | — | 1 | 8.22 |
| CHEMBL430429 | — | — | 1 | 8.15 |
| CHEMBL4569734 | — | — | 1 | 7.52 |
| CHEMBL4554054 | — | — | 1 | 5.96 |
| CHEMBL4579879 | — | — | 1 | 5.77 |
| CHEMBL260046 | EVOFOSFAMIDE | 3.0 | 1 | 5.70 |
| CHEMBL4532906 | — | — | 1 | 5.64 |
| CHEMBL4476092 | — | — | 1 | 5.57 |
| CHEMBL4459263 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4530380 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL430429 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL4569734 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4554054 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL4579879 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL260046 | EVOFOSFAMIDE | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4532906 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL4476092 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL4459263 | — | IC50 | = | 9300.0 | nM | 5.03 |