Assay Detail
Functional
CHEMBL4316865
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Antiproliferative activity against human JIMT1 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | JIMT-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A comprehensive review of salinomycin derivatives as potent anticancer and anti-CSCs agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.51 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1208572 | SALINOMYCIN | 2.0 | 1 | 6.28 |
| CHEMBL4540622 | — | — | 1 | 6.00 |
| CHEMBL4462434 | — | — | 1 | 5.57 |
| CHEMBL4468593 | — | — | 1 | 4.90 |
| CHEMBL4567686 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1208572 | SALINOMYCIN | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL4540622 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4462434 | — | IC50 | = | 2680.0 | nM | 5.57 |
| CHEMBL4468593 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL4567686 | — | IC50 | = | 15600.0 | nM | 4.81 |