Assay Detail
Functional
CHEMBL4317089
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Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of new derivatives of boehmeriasin A and their biological evaluation in liver cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.59 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446479 | — | — | 1 | 9.00 |
| CHEMBL1958071 | — | — | 1 | 8.30 |
| CHEMBL4439007 | — | — | 1 | 7.80 |
| CHEMBL1958076 | — | — | 1 | 7.68 |
| CHEMBL4443083 | — | — | 1 | 5.16 |
| CHEMBL4438041 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446479 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1958071 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL4439007 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL1958076 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL4443083 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL4438041 | — | IC50 | - | — | - |