Assay Detail
Functional
CHEMBL4317094
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Cytotoxicity against human FOCUS cells after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of new derivatives of boehmeriasin A and their biological evaluation in liver cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.97 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446479 | — | — | 1 | 7.92 |
| CHEMBL1958071 | — | — | 1 | 7.70 |
| CHEMBL4443083 | — | — | 1 | 5.30 |
| CHEMBL4438041 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446479 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL1958071 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4443083 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4438041 | — | IC50 | - | — | - |