Assay Detail
ADMET
CHEMBL4320547
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Cytotoxicity against HEK293T cells assessed as cell death after 18 to 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.88 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL412927 | MELITTIN | — | 1 | 5.61 |
| CHEMBL4585680 | — | — | 1 | 4.72 |
| CHEMBL4470551 | — | — | 1 | 4.32 |
| CHEMBL4458132 | — | — | 1 | - |
| CHEMBL4474667 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL412927 | MELITTIN | IC50 | = | 2484.0 | nM | 5.61 |
| CHEMBL4585680 | — | IC50 | = | 19210.0 | nM | 4.72 |
| CHEMBL4470551 | — | IC50 | = | 47400.0 | nM | 4.32 |
| CHEMBL4458132 | — | IC50 | = | 5921000.0 | nM | - |
| CHEMBL4474667 | — | IC50 | = | 324000.0 | nM | - |