Assay Detail
Binding
CHEMBL4322020
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mouse Nav1.7 by radioligand binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 9 subunit alpha (CHEMBL3414411) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na<sub>V</sub>1.7.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.27 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4444707 | — | — | 1 | 8.68 |
| CHEMBL4471012 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4444707 | — | Kd | = | 2.1 | nM | 8.68 |
| CHEMBL4471012 | — | Kd | = | 14.0 | nM | 7.85 |