Assay Detail
Binding
CHEMBL4322091
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human JAK1 using poly[Glu:Tyr] (4:1) substrate preincubated for 20 mis followed by addition of ATP and measured after 120 mins in presence of 33P-gamma ATP by hotspot kinase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Overview of Recent Strategic Advances in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.56 | 5.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3622376 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3622376 | — | IC50 | = | 2728.0 | nM | 5.56 |