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Assay Detail

CHEMBL4322123

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to renin (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Renin (CHEMBL286)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Why Some Targets Benefit from beyond Rule of Five Drugs.
Egbert M, Whitty A, Keserű GM, Vajda S.
J Med Chem (2019) 62 : 10005 -10025
PubMed 31188592 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.88 9.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL31601 REMIKIREN 2.0 1 9.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL31601 REMIKIREN Kd = 0.131 nM 9.88