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Assay Detail

CHEMBL4322149

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GST-tagged PI3K gamma mutant (unknown origin) expressed in HEK293 cells after 15 mins by immunoblot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Why Some Targets Benefit from beyond Rule of Five Drugs.
Egbert M, Whitty A, Keserű GM, Vajda S.
J Med Chem (2019) 62 : 10005 -10025
PubMed 31188592 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.38 8.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL428496 WORTMANNIN 1 8.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL428496 WORTMANNIN Ki = 4.2 nM 8.38