Assay Detail
Binding
CHEMBL4322158
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human TASK1 by whole cell voltage clamp assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Potassium channel subfamily K member 3 (CHEMBL2321613) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
TASK Channels Pharmacology: New Challenges in Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.08 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4592278 | — | — | 1 | 6.66 |
| CHEMBL1557966 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4592278 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL1557966 | — | IC50 | = | 3200.0 | nM | 5.50 |