Assay Detail
Binding
CHEMBL4322244
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Reversible inhibition of Trypanosoma cruzi cruzipain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.17 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1288532 | — | — | 1 | 9.40 |
| CHEMBL4557939 | — | — | 1 | 9.10 |
| CHEMBL1288523 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1288532 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL4557939 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL1288523 | — | IC50 | = | 1.0 | nM | 9.00 |