Assay Detail
ADMET
CHEMBL4322246
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Reversible inhibition of human cathepsin B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.02 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1288523 | — | — | 1 | 8.05 |
| CHEMBL1288532 | — | — | 1 | 7.06 |
| CHEMBL4557939 | — | — | 1 | 5.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1288523 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL1288532 | — | IC50 | = | 87.0 | nM | 7.06 |
| CHEMBL4557939 | — | IC50 | = | 1111.0 | nM | 5.95 |