Assay Detail

CHEMBL4323656

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Binding

Inhibition of Clostridium difficile toxin B

ChEMBL ↗

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Target

Toxin B (CHEMBL3580505) ↗

Open DB target context

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Toxin B (CHEMBL3580505) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Toxin B

CHEMBL3580505

Anchored from Assay target.

Protein identity Toxin B

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Clostridioides difficile
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Toxin B (CHEMBL3580505) ↗

Type	SINGLE PROTEIN
Organism	Peptoclostridium difficile

Publication

Development and Therapeutic Potential of Selenazo Compounds.

Ruberte AC, Sanmartin C, Aydillo C, Sharma AK, Plano D.
J Med Chem (2020) 63 : 1473 -1489
PubMed 31638805 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.76	7.76

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL51085	EBSELEN	3.0	1	7.76

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL51085	EBSELEN	IC50	=	17.2	nM	7.76