Assay Detail
Binding
CHEMBL4323773
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to alphaVbeta3 integrin receptor (unknown origin) incubated fro 30 mins by competitive solid-phase binding assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.01 | 8.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4454796 | — | — | 1 | 8.47 |
| CHEMBL4469125 | — | — | 1 | 8.02 |
| CHEMBL4446073 | — | — | 1 | 7.54 |
| CHEMBL4534088 | — | — | 1 | - |
| CHEMBL4442651 | — | — | 1 | - |
| CHEMBL4575577 | — | — | 1 | - |
| CHEMBL4593469 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4454796 | — | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL4469125 | — | IC50 | = | 9.5 | nM | 8.02 |
| CHEMBL4446073 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL4534088 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4442651 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4575577 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4593469 | — | IC50 | > | 1000.0 | nM | - |