Assay Detail
Binding
CHEMBL4324282
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NS5A in HCV genotype 3a by cell based luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus subtype 3a |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.39 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2374220 | LEDIPASVIR | 4.0 | 1 | 7.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2374220 | LEDIPASVIR | IC50 | = | 41.0 | nM | 7.39 |