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Assay Detail

CHEMBL4324448

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Functional
Antiproliferative activity against human MCF7:TAM1 cells assessed as reduction in cell viability after 24 hs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7:TAM1
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7:TAM1 (CHEMBL4630717)
Type CELL-LINE
Organism Homo sapiens

Publication

Indole-based melatonin analogues: Synthetic approaches and biological activity.
Wang SY, Shi XC, Laborda P.
Eur J Med Chem (2020) 185 : 111847 -111847
PubMed 31727472 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4443331 1 5.40
CHEMBL4475977 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4443331 IC50 = 4000.0 nM 5.40
CHEMBL4475977 IC50 = 4000.0 nM 5.40