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Assay Detail

CHEMBL4324674

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CXCR2-mediated chemotaxis in mouse BAF3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type BaF3
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

C-X-C chemokine receptor type 2 (CHEMBL4105830)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Targeting CXCR1/2: The medicinal potential as cancer immunotherapy agents, antagonists research highlights and challenges ahead.
Che J, Song R, Chen B, Dong X.
Eur J Med Chem (2020) 185 : 111853 -111853
PubMed 31732253 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4462143 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4462143 IC50 = 0.1 nM 10.00