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Assay Detail

CHEMBL4326706

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of TTBK2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tau-tubulin kinase 2 (CHEMBL3337327)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tau Tubulin Kinase 1 (TTBK1), a new player in the fight against neurodegenerative diseases.
Nozal V, Martinez A.
Eur J Med Chem (2019) 161 : 39 -47
PubMed 30342424 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4528881 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4528881 IC50 = 170.0 nM 6.77