Assay Detail
Functional
CHEMBL4326759
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Antiprotozoal activity against chloroquine-sensitive Plasmodium falciparum D6
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinoline and quinolone dimers and their biological activities: An overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 8.93 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4218834 | — | — | 1 | 9.00 |
| CHEMBL335524 | — | — | 1 | 8.92 |
| CHEMBL138071 | — | — | 1 | 8.92 |
| CHEMBL42527 | — | — | 1 | 8.92 |
| CHEMBL342178 | — | — | 1 | 8.92 |
| CHEMBL46524 | — | — | 1 | 8.92 |
| CHEMBL336448 | — | — | 1 | 8.92 |
| CHEMBL424284 | — | — | 1 | 8.92 |
| CHEMBL136459 | — | — | 1 | 8.92 |
| CHEMBL137686 | — | — | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4218834 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL335524 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL138071 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL42527 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL342178 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL46524 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL336448 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL424284 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL136459 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL137686 | — | IC50 | = | 1.2 | nM | 8.92 |