Assay Detail
Functional
CHEMBL4326795
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Antiproliferative activity against human SUIT2 cells after 72 hrs by prestoblue assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.92 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4439395 | — | — | 1 | 6.68 |
| CHEMBL445813 | AT-7519 | 2.0 | 1 | 6.25 |
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 4.83 |
| CHEMBL4541682 | — | — | 1 | - |
| CHEMBL4553956 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4439395 | — | IC50 | = | 209.0 | nM | 6.68 |
| CHEMBL445813 | AT-7519 | IC50 | = | 557.0 | nM | 6.25 |
| CHEMBL14762 | SELICICLIB | IC50 | = | 14801.0 | nM | 4.83 |
| CHEMBL4541682 | — | IC50 | > | 2000.0 | nM | - |
| CHEMBL4553956 | — | IC50 | > | 2000.0 | nM | - |