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Assay Detail

CHEMBL4326799

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK9 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 9 (CHEMBL3116)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy.
Rana S, Sonawane YA, Taylor MA, Kizhake S, Zahid M, Natarajan A.
Bioorg Med Chem Lett (2018) 28 : 3736 -3740
PubMed 30343954 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.04 6.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4439395 1 6.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4439395 IC50 = 911.0 nM 6.04