Assay Detail
Functional
CHEMBL4327229
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Antiproliferative activity against human HT-29 cells by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Research advances on anticancer activities of matrine and its derivatives: An updated overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.75 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2031194 | — | — | 1 | 5.04 |
| CHEMBL4450736 | — | — | 1 | 4.88 |
| CHEMBL4463492 | — | — | 1 | 4.75 |
| CHEMBL2031192 | — | — | 1 | 4.56 |
| CHEMBL204860 | MATRINE | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2031194 | — | IC50 | = | 9050.0 | nM | 5.04 |
| CHEMBL4450736 | — | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL4463492 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL2031192 | — | IC50 | = | 27800.0 | nM | 4.56 |
| CHEMBL204860 | MATRINE | IC50 | = | 28600.0 | nM | 4.54 |