Assay Detail
ADMET
CHEMBL4327293
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Cytotoxicity against HFF
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of novel quinazoline derivatives as potent antiplasmodial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.35 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231795 | — | — | 1 | 5.64 |
| CHEMBL4461581 | — | — | 1 | 5.49 |
| CHEMBL3426803 | — | — | 1 | 5.48 |
| CHEMBL569864 | — | — | 1 | 5.30 |
| CHEMBL4527662 | — | — | 1 | 5.25 |
| CHEMBL4558658 | — | — | 1 | 5.14 |
| CHEMBL4537137 | — | — | 1 | 5.14 |
| CHEMBL4550522 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231795 | — | IC50 | = | 2286.0 | nM | 5.64 |
| CHEMBL4461581 | — | IC50 | = | 3215.0 | nM | 5.49 |
| CHEMBL3426803 | — | IC50 | = | 3295.0 | nM | 5.48 |
| CHEMBL569864 | — | IC50 | = | 4997.0 | nM | 5.30 |
| CHEMBL4527662 | — | IC50 | = | 5629.0 | nM | 5.25 |
| CHEMBL4558658 | — | IC50 | = | 7170.0 | nM | 5.14 |
| CHEMBL4537137 | — | IC50 | = | 7210.0 | nM | 5.14 |
| CHEMBL4550522 | — | IC50 | > | 10000.0 | nM | - |