Assay Detail
Binding
CHEMBL4328306
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bone morphogenetic protein receptor type-1A (CHEMBL5275) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.63 | 7.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513147 | — | — | 1 | 7.63 |
| CHEMBL388978 | STAUROSPORINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513147 | — | IC50 | = | 23.4 | nM | 7.63 |
| CHEMBL388978 | STAUROSPORINE | IC50 | - | — | - |