Assay Detail
Binding
CHEMBL4328895
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human COX-2 transfected in CHO cells using arachidonic acid as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Medicinal chemistry of vicinal diaryl scaffold: A mini review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.45 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL146742 | — | — | 1 | 7.80 |
| CHEMBL416146 | ETORICOXIB | 4.0 | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL146742 | — | IC50 | = | 16.0 | nM | 7.80 |
| CHEMBL416146 | ETORICOXIB | IC50 | = | 81.0 | nM | 7.09 |