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Assay Detail

CHEMBL4328898

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of COX-2 (unknown origin) expressed in CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prostaglandin G/H synthase 2 (CHEMBL230)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Medicinal chemistry of vicinal diaryl scaffold: A mini review.
Ramajayam R.
Eur J Med Chem (2019) 162 : 1 -17
PubMed 30396033 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.96 6.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL275664 1 6.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL275664 IC50 = 110.0 nM 6.96