Assay Detail
Binding
CHEMBL4328909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine brain microtubule polymerization measured up to 30 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Medicinal chemistry of vicinal diaryl scaffold: A mini review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.52 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45512 | — | — | 1 | 6.17 |
| CHEMBL297677 | — | — | 1 | 6.10 |
| CHEMBL47306 | — | — | 1 | 5.75 |
| CHEMBL376684 | — | — | 1 | 5.20 |
| CHEMBL221473 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45512 | — | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL297677 | — | IC50 | = | 790.0 | nM | 6.10 |
| CHEMBL47306 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL376684 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL221473 | — | IC50 | = | 41500.0 | nM | 4.38 |