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Assay Detail

CHEMBL4329067

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Reversible inhibition of human MAOB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-tert-Pentylphenoxyalkyl derivatives - Histamine H<sub>3</sub> receptor ligands and monoamine oxidase B inhibitors.
Łażewska D, Olejarz-Maciej A, Kaleta M, Bajda M, Siwek A, Karcz T, Doroz-Płonka A, Cichoń U, Kuder K, Kieć-Kononowicz K.
Bioorg Med Chem Lett (2018) 28 : 3596 -3600
PubMed 30404719 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.05 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL396778 SAFINAMIDE 4.0 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL396778 SAFINAMIDE IC50 = 9.0 nM 8.05