Assay Detail
Binding
CHEMBL4331193
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ASCT2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neutral amino acid transporter B(0) (CHEMBL3562162) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery and development of small molecule modulators targeting glutamine metabolism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.02 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3754053 | — | — | 1 | 5.02 |
| CHEMBL6251 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3754053 | — | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL6251 | — | IC50 | = | 1200000.0 | nM | - |