Assay Detail
Functional
CHEMBL4331303
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Cytotoxicity against mouse LL/2 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Lewis lung carcinoma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.55 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.00 |
| CHEMBL4550214 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4550214 | — | IC50 | = | 7870.0 | nM | 5.10 |