Assay Detail
Binding
CHEMBL4331759
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RON (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Macrophage-stimulating protein receptor (CHEMBL2689) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting the immunity protein kinases for immuno-oncology.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.45 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL460702 | BMS-777607 | 2.0 | 1 | 8.74 |
| CHEMBL2323775 | MK-8033 | 1.0 | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL460702 | BMS-777607 | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL2323775 | MK-8033 | IC50 | = | 7.0 | nM | 8.15 |