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Assay Detail

CHEMBL4332930

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using beetle luciferin as substrate after 1 hr by MAO-Glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL1951)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of selective and reversible LSD1 inhibitors with anti-metastasis activity by high-throughput docking.
Li L, Li R, Wang Y.
Bioorg Med Chem Lett (2019) 29 : 544 -548
PubMed 30611617 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.07 7.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3989843 TRANYLCYPROMINE 4.0 1 7.07
CHEMBL4448235 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3989843 TRANYLCYPROMINE IC50 = 85.0 nM 7.07
CHEMBL4448235 IC50 > 200000.0 nM -