Assay Detail
Binding
CHEMBL4333217
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Inhibition of Bach1-Mafk interaction (unknown origin) by luciferase reporter gene based enzyme fragment complementation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.15 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4474353 | — | — | 1 | 5.50 |
| CHEMBL48802 | SULFORAPHANE | 3.0 | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4474353 | — | IC50 | = | 3162.28 | nM | 5.50 |
| CHEMBL48802 | SULFORAPHANE | IC50 | = | 15848.93 | nM | 4.80 |