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Assay Detail

CHEMBL4333722

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Binding
Inhibition of xanthine oxidase (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL1929)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors.
Xu X, Deng L, Nie L, Chen Y, Liu Y, Xie R, Li Z.
Bioorg Med Chem Lett (2019) 29 : 525 -528
PubMed 30630716 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.24 8.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL169526 1 8.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL169526 IC50 = 5.8 nM 8.24