Assay Detail
Functional
CHEMBL4333750
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Antifungal activity against azole-resistant Candida albicans after 24 hrs by resazurin dye based fluorimetric assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antimicrobial activities of N<sup>6</sup>-hydroxyagelasine analogs and revision of the structure of ageloximes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.73 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1463 | FLUCYTOSINE | 4.0 | 1 | 6.39 |
| CHEMBL4592498 | — | — | 1 | 5.70 |
| CHEMBL4469221 | — | — | 1 | 5.10 |
| CHEMBL4443174 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1463 | FLUCYTOSINE | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL4592498 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4469221 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL4443174 | — | IC50 | > | 64000.0 | nM | - |