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Assay Detail

CHEMBL4333763

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of Staphylococcus epidermidis ATCC 35984
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Staphylococcus epidermidis
Confidence 1 — Organism
Curated By Autocuration

Target

Staphylococcus epidermidis (CHEMBL353)
Type ORGANISM
Organism Staphylococcus epidermidis

Publication

Synthesis and antimicrobial activities of N<sup>6</sup>-hydroxyagelasine analogs and revision of the structure of ageloximes.
Paulsen B, Fredriksen KA, Petersen D, Maes L, Matheeussen A, Naemi AO, Scheie AA, Simm R, Ma R, Wan B, Franzblau S, Gundersen LL.
Bioorg Med Chem (2019) 27 : 620 -629
PubMed 30638761 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.20 4.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4469221 1 4.20
CHEMBL4592498 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4469221 IC50 = 63000.0 nM 4.20
CHEMBL4592498 IC50 = 125000.0 nM -