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Assay Detail

CHEMBL4333880

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

A mitochondria-targeted organic arsenical accelerates mitochondrial metabolic disorder and function injury.
Fan XY, Liu YJ, Cai YM, Wang AD, Xia YZ, Hu YJ, Jiang FL, Liu Y.
Bioorg Med Chem (2019) 27 : 760 -768
PubMed 30665675 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.20 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4450700 1 5.35
CHEMBL3290761 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4450700 IC50 = 4440.0 nM 5.35
CHEMBL3290761 IC50 = 9000.0 nM 5.05