Assay Detail
Functional
CHEMBL4334048
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Human rhinovirus 1B infected in human HeLa cells assessed as reduction in virus-induced cytopathic effect after 2 days by SRB staining based microscopic method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human rhinovirus 1B |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lignan Dimers from Forsythia viridissima Roots and Their Antiviral Effects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.48 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4464292 | — | — | 1 | 4.89 |
| CHEMBL425148 | MATAIRESINOL | — | 1 | 4.37 |
| CHEMBL4473882 | — | — | 1 | 4.34 |
| CHEMBL4467052 | — | — | 1 | 4.32 |
| CHEMBL20210 | RUPINTRIVIR | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4464292 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL425148 | MATAIRESINOL | IC50 | = | 43200.0 | nM | 4.37 |
| CHEMBL4473882 | — | IC50 | = | 45700.0 | nM | 4.34 |
| CHEMBL4467052 | — | IC50 | = | 47500.0 | nM | 4.32 |
| CHEMBL20210 | RUPINTRIVIR | IC50 | - | — | - |